abstract：:Inflammation is critical in the dysregulated growth of adipose tissue and associated vascular dysfunctions. 15-Lipoxygenase metabolites, important mediators of inflammation in adipose tissue during obese conditions, may contribute to codependence of inflammation and angiogenesis in adipose tissue. We have already repo...

journal_title：PeerJ

authors： Soumya SJ,Binu S,Helen A,Reddanna P,Sudhakaran PR

更新日期：2014-10-21 00:00:00

abstract：:The capacity for aerial maneuvering was likely a major influence on the evolution of flying animals. Here we evaluate consequences of paravian morphology for aerial performance by quantifying static stability and control effectiveness of physical models for numerous taxa sampled from within the lineage leading to bird...

journal_title：PeerJ

authors： Evangelista D,Cam S,Huynh T,Kwong A,Mehrabani H,Tse K,Dudley R

更新日期：2014-10-16 00:00:00

abstract：:We demonstrated that the 3-substituted benzothiophene-1,1-dioxide class of compounds are effective inhibitors of Mycobacterium tuberculosis growth under aerobic conditions. We examined substitution at the C-3 position of the benzothiophene-1,1-dioxide series systematically to delineate structure-activity relationships...

journal_title：PeerJ

authors： Chandrasekera NS,Bailey MA,Files M,Alling T,Florio SK,Ollinger J,Odingo JO,Parish T

更新日期：2014-10-07 00:00:00

abstract：:Meniscal tears are a common cause of stifle lameness in dogs. Use of autologous synoviocytes from the affected stifle is an attractive cell source for tissue engineering replacement fibrocartilage. However, the diseased state of these cells may impede in vitro fibrocartilage formation. Synoviocytes from 12 osteoarthri...

journal_title：PeerJ

authors： Warnock JJ,Bobe G,Duesterdieck-Zellmer KF

更新日期：2014-09-30 00:00:00

abstract：:Metabolic dysfunction in skeletal muscle is a major contributor to the development of type 2 diabetes. Endurance exercise training has long been established as an effective means to directly restore skeletal muscle glucose and lipid uptake and metabolism. However, in addition to the direct effects of skeletal muscle o...

journal_title：PeerJ

authors： Peterson JM,Mart R,Bond CE

更新日期：2014-09-30 00:00:00

abstract：:Atoposaurid crocodyliforms represent an important faunal component of Late Jurassic to Early Cretaceous Laurasian semi-aquatic to terrestrial ecosystems, with numerous spatiotemporally contemporaneous atoposaurids known from western Europe. In particular, the Late Jurassic of France and Germany records evidence for hi...

journal_title：PeerJ

authors： Tennant JP,Mannion PD

更新日期：2014-09-25 00:00:00

abstract：:Background. Little is known about the characteristics of internet distractions that students may engage in during lecture. The objective of this pilot study is to identify some of the internet-based distractions students engage in during in-person lectures. The findings will help identify what activities most commonly...

journal_title：PeerJ

authors： Nalliah RP,Allareddy V

更新日期：2014-09-16 00:00:00

abstract：:Ocean acidification (OA) is not an isolated threat, but acts in concert with other impacts on ecosystems and species. Coastal marine invertebrates will have to face the synergistic interactions of OA with other global and local stressors. One local factor, common in coastal environments, is trace element contamination...

journal_title：PeerJ

authors： Horwitz R,Borell EM,Fine M,Shaked Y

更新日期：2014-09-09 00:00:00

abstract：:The aim of this study was to analyze the influence of smoking habits and other possibly relevant factors on dental implant survival. The study population included all patients who underwent dental implants between the years 1999 and 2008 at a large military dental clinic and were examined in the periodic medical exami...

journal_title：PeerJ

authors： Twito D,Sade P

更新日期：2014-09-02 00:00:00

abstract：:The threatened status (both ecologically and legally) of Caribbean staghorn coral, Acropora cervicornis, has prompted rapidly expanding efforts in culture and restocking, although tissue loss diseases continue to affect populations. In this study, disease surveillance and histopathological characterization were used t...

journal_title：PeerJ

authors： Miller MW,Lohr KE,Cameron CM,Williams DE,Peters EC

更新日期：2014-08-28 00:00:00

abstract：:The prevalence of pre-diabetes (PD) among US adults has increased substantially over the past two decades. By current estimates, over 34% of US adults fall in the PD category, 84% of whom meet the American Diabetes Association's criteria for impaired fasting glucose (IFG). Low physical activity (PA) and/or sedentary b...

journal_title：PeerJ

authors： Farni K,Shoham DA,Cao G,Luke AH,Layden J,Cooper RS,Dugas LR

更新日期：2014-08-19 00:00:00

abstract：:Among helminth parasites, Paragonimus (zoonotic lung fluke) gains considerable importance from veterinary and medical points of view because of its diversified effect on its host. Nearly fifty species of Paragonimus have been described across the globe. It is estimated that more than 20 million people are infected wor...

journal_title：PeerJ

authors： Biswal DK,Chatterjee A,Bhattacharya A,Tandon V

更新日期：2014-08-12 00:00:00

abstract：:In humans and apes, yawn contagion echoes emotional contagion, the basal layer of empathy. Hence, yawn contagion is a unique tool to compare empathy across species. If humans are the most empathic animal species, they should show the highest empathic response also at the level of emotional contagion. We gathered data ...

journal_title：PeerJ

authors： Palagi E,Norscia I,Demuru E

更新日期：2014-08-12 00:00:00

abstract：:The structural and material properties of insect cuticle remain largely unexplored, even though they comprise the majority (approximately 80%) of animals. Insect cuticle serves many functions, including protection against predatory attacks, which is especially beneficial to species failing to employ effective running ...

journal_title：PeerJ

authors： Clark AJ,Triblehorn JD

更新日期：2014-07-31 00:00:00

abstract：:The term autobiographical self has been used to refer to a mental state that permits reflection on self-identity and personality and the answer to related questions (Damasio, 1998). It requires the retrieval and integrated assembly of memories of facts and events that define an individual's biography. The neural mecha...

journal_title：PeerJ

authors： Araujo HF,Kaplan J,Damasio H,Damasio A

更新日期：2014-07-22 00:00:00

abstract：:Automatic species classification of birds from their sound is a computational tool of increasing importance in ecology, conservation monitoring and vocal communication studies. To make classification useful in practice, it is crucial to improve its accuracy while ensuring that it can run at big data scales. Many appro...

journal_title：PeerJ

authors： Stowell D,Plumbley MD

更新日期：2014-07-17 00:00:00

abstract：:The maximum likelihood estimation (MLE) method, typically used for polytomous logistic regression, is prone to bias due to both misclassification in outcome and contamination in the design matrix. Hence, robust estimators are needed. In this study, we propose such a method for nominal response data with continuous cov...

journal_title：PeerJ

authors： Wang X

更新日期：2014-07-01 00:00:00

abstract：:Single-cell analysis has the potential to provide us with a host of new knowledge about biological systems, but it comes with the challenge of correctly interpreting the biological information. While emerging techniques have made it possible to measure inter-cellular variability at the transcriptome level, no consensu...

journal_title：PeerJ

authors： Kippner LE,Kim J,Gibson G,Kemp ML

更新日期：2014-06-24 00:00:00

abstract：:The partitioning of production forests into discretely managed forest stands confronts animals with diversity in forest attributes at scales from point-level tree assemblages to distinct forest patches and range-level forest cover. We have investigated the movement and ranging patterns of male Common Chaffinches, Frin...

journal_title：PeerJ

authors： Kubiczek K,Renner SC,Böhm SM,Kalko EK,Wells K

更新日期：2014-06-19 00:00:00

abstract：:Accommodation resistance is a training technique that may improve strength and power gains beyond those achieved by traditional free weights. In this method, chains are either added on a free-weight bar and combined with traditional plates or added to the bar as the entire load. Purpose. The aim of the current study w...

journal_title：PeerJ

authors： Ataee J,Koozehchian MS,Kreider RB,Zuo L

更新日期：2014-06-17 00:00:00

abstract：:The cost of enzymes makes enzymatic hydrolysis one of the most expensive steps in the production of lignocellulosic ethanol. Diverse studies have used commercial enzyme cocktails assuming that change in total protein concentration during hydrolysis was solely due to adsorption of endo- and exoglucanases onto the subst...

journal_title：PeerJ

authors： Rosales-Calderon O,Trajano HL,Duff SJ

更新日期：2014-06-10 00:00:00

abstract：:Background. Many Long-Term Care (LTC) institutionalized patients are the most frail and functionally dependent among the geriatric population and have significant oral health disparities.They often suffer from dental neglect due to limited access to appropriate professional dental care. These patients have chronic hea...

journal_title：PeerJ

authors： Bilder L,Yavnai N,Zini A

更新日期：2014-06-10 00:00:00

abstract：:Wing pigmentation in Calopteryx damselflies, caused by the deposition of melanin, is energetically expensive to produce and enhances predation risk. However, patterns of melanisation are used in species identification, greater pigmentation is an accurate signal of male immune function in at least some species, and the...

journal_title：PeerJ

authors： Hassall C

更新日期：2014-06-10 00:00:00

abstract：:Background. Nasal continuous positive airway pressure (nCPAP) is a widely accepted technique of non-invasive respiratory support in premature infants with respiratory distress syndrome due to lack of lung surfactant. If this approach fails, the next step is often intubation, mechanical ventilation (MV) and intratrache...

journal_title：PeerJ

authors： Walther FJ,Hernández-Juviel JM,Waring AJ

更新日期：2014-05-27 00:00:00

abstract：:Freshwater food webs are dominated by aquatic invertebrates whose trophic relationships are often poorly known. Here, I used laboratory experiments to study the role of a water bug, Sigara striata, as a potential predator and prey in food webs of stagnant waters. Multiple-choice predation experiment revealed that Siga...

journal_title：PeerJ

authors： Klecka J

更新日期：2014-05-22 00:00:00

abstract：:We studied the impact of simulated global change on a high alpine meadow plant community. Specifically, we examined whether short-term (5 years) responses are good predictors for medium-term (7 years) changes in the system by applying a factorial warming and nutrient manipulation to 20 plots in Latnjajaure, subarctic ...

journal_title：PeerJ

authors： Alatalo JM,Little CJ,Jägerbrand AK,Molau U

更新日期：2014-05-22 00:00:00

abstract：:Background. Eucryptodiran turtles from the Late Jurassic (mainly Kimmeridgian) deposits of the Jura Mountains (Switzerland and France) are among the earliest named species traditionally referred to the Plesiochelyidae, Thalassemydidae, and Eurysternidae. As such, they are a reference for the study of Late Jurassic euc...

journal_title：PeerJ

authors： Anquetin J,Püntener C,Billon-Bruyat JP

更新日期：2014-05-13 00:00:00

abstract：:We examine heritability estimation of an ordinal trait for osteoarthritis, using a population of pig-tailed macaques from the Washington National Primate Research Center (WaNPRC). This estimation is non-trivial, as the data consist of ordinal measurements on 16 intervertebral spaces throughout each macaque's spinal co...

journal_title：PeerJ

authors： Chi PB,Duncan AE,Kramer PA,Minin VN

更新日期：2014-05-01 00:00:00

abstract：:Because microorganisms are sensitive to temperature, ongoing global warming is predicted to influence microbial community structure and function. We used large-scale warming experiments established at two sites near the northern and southern boundaries of US eastern deciduous forests to explore how microbial communiti...

journal_title：PeerJ

authors： Cregger MA,Sanders NJ,Dunn RR,Classen AT

更新日期：2014-04-24 00:00:00

abstract：:Aerobic activity levels increase with body temperature across vertebrates. Differences in these levels, from highly active to sedentary, are reflected in their ecology and behavior. Yet, the changes in the cardiovascular system that allow for greater oxygen supply at higher temperatures, and thus greater aerobic activ...

journal_title：PeerJ

authors： Gillooly JF,Zenil-Ferguson R

更新日期：2014-04-10 00:00:00

abstract：:With rising environmental concerns on potable water safety and eutrophication, increased media attention and tighter environmental regulations, managing animal waste in an environmentally responsible and economically feasible way can be a challenge. In this study, the possibility of using granular anammox process for ...

journal_title：PeerJ

authors： Ni SQ,Yang N

更新日期：2014-04-08 00:00:00

abstract：:Purpose. People with stroke living in the community have an increased prevalence of depression and lower quality of life than healthy older adults. This cross-sectional observational study investigated whether participation in regular exercise was associated with improved mood and quality of life. Methods. We recruite...

journal_title：PeerJ

authors： McDonnell MN,Mackintosh SF,Hillier SL,Bryan J

更新日期：2014-03-27 00:00:00

abstract：:Garden Warblers Sylvia borin were studied during autumn stopover in Crete before crossing the barrier of the Mediterranean Sea and the Sahara Desert. Birds followed with transmitters show extensive stopover periods, which were longer in first-year birds, 16 days, compared with adult birds, 14 days. The distribution of...

journal_title：PeerJ

authors： Barboutis C,Henshaw I,Kullberg C,Nikolopoulou S,Fransson T

更新日期：2014-03-25 00:00:00

abstract：:The mutant form GGBP/H152C of the D-glucose/D-galactose-binding protein with the solvatochromic dye BADAN linked to cysteine residue Cys 152 can be used as a potential base for a sensitive element of glucose biosensor system. We investigated the influence of various external factors on the physical-chemical properties...

journal_title：PeerJ

authors： Fonin AV,Stepanenko OV,Povarova OI,Volova CA,Philippova EM,Bublikov GS,Kuznetsova IM,Demchenko AP,Turoverov KK

更新日期：2014-03-18 00:00:00

abstract：:The eukaryotic polypyrimidine tract binding protein (PTB) serves primarily as a regulator of alternative splicing of messenger RNA, but is also co-opted to other roles such as RNA localisation and translation initiation from internal ribosome entry sites. The neuronal paralogue of PTB (nPTB) is 75% identical in amino ...

journal_title：PeerJ

authors： Joshi A,Esteve V,Buckroyd AN,Blatter M,Allain FH,Curry S

更新日期：2014-03-13 00:00:00

abstract：:Following a radiation incident, preliminary dose estimates made by γ-H2AX foci analysis can supplement the early triage of casualties based on clinical symptoms. Sample processing time is important when many individuals need to be rapidly assessed. A protocol was therefore developed for high sample throughput that req...

journal_title：PeerJ

authors： Moquet J,Barnard S,Rothkamm K

更新日期：2014-03-06 00:00:00

abstract：:Species traits may provide a short-cut to predicting generalities in species turnover in response to environmental change, particularly for poorly known taxa. We ask if morphological traits of assemblages respond predictably to macrohabitats across a large scale. Ant assemblages were collected at nine paired pasture a...

journal_title：PeerJ

authors： Yates ML,Andrew NR,Binns M,Gibb H

更新日期：2014-03-04 00:00:00

abstract：:Background. Neonatal hyperbilirubinemia (HB) may cause severe neurological damage, but serious consequences are effectively controlled by phototherapy and blood exchange transfusion. HB is still a serious health problem in economically compromised parts of the world. The long term outcome has been regarded favorable b...

journal_title：PeerJ

authors： Hokkanen L,Launes J,Michelsson K

更新日期：2014-03-04 00:00:00

abstract：:Background. The impact of head and neck cancer (HNC) in long-term survivors differs widely among individuals, and a significant number of them suffer from the negative effects of disease, whereas others report significant positive effect. This systematic review investigated the evidence the implications of treatment f...

journal_title：PeerJ

authors： Harding S,Sanipour F,Moss T

更新日期：2014-02-11 00:00:00

abstract：:Language WorkBenches (LWBs) are software engineering tools that help domain experts develop solutions to various classes of problems. Some of these tools focus on non-technical users and provide languages to help organize knowledge while other workbenches provide means to create new programming languages. A key advant...

journal_title：PeerJ

authors： Simi M,Campagne F

更新日期：2014-01-02 00:00:00